Pamel

Indication:

Pamel (Pantoprazole) is indicated where suppression of acid secretion is of therapeutic benefit. Pamel (Pantoprazole) is registered for the following indications:

Ø  Peptic ulcer diseases (PUD)

Ø  Gastro esophageal reflux diseases (GERD)

Ø  Treatment of ulcer resistant to H2 receptor antagonists (H2RAs)

Ø  Treatment of ulcers induced by non-steroidal anti-inflammatory drugs (NSAIDs)

Ø  Gastrointestinal (GI) bleeding from stress or acid peptic diseases

Ø  Eradication of Helicobacter pylori (in combination with antibiotics)

Ø  Zollinger-Ellison syndrome

Ø  Prophylaxis for acid aspiration syndrome during induction of anaesthesia

Dosage & Administration:

Ø  Gastro esophageal reflux disease, 20-40 mg daily for 4 weeks continued for further 4 weeks if not fully healed; may be continued at 20 mg daily ( long-time management), increased to 40 mg daily if symptoms return.

Ø  Duodenal ulcer, 40 mg daily for 2 weeks, continued for further 2 weeks if not fully healed.

Ø  Duodenal ulcer associated with Helicobacter pylori, Pantoprazole 20 mg 3-4 times daily in combination with appropriate antibiotic. NSAID-induced peptic ulcer: 20 mg daily.

Ø  Zollinger-Ellison Syndrome, the recommended oral dosage is one gastro-resistant pantoprazole tablet 20 mg twice daily.

Preparation:

Pamel 20 Tablet: Each enteric coated tablet contains Pantoprazole Sodium Sesquihydrate INN equivalent to Pantoprazole 20 mg.

Pamel 40 Tablet: Each enteric coated tablet contains Pantoprazole Sodium Sesquihydrate INN equivalent to Pantoprazole 40 mg.