Medizol

Metronidazole Benzoate

Anti-Amoebics

Indication:

● All forms of amoebiasis (intestinal and extra-intestinal disease including liver abscess and that of symptomless cyst passers) ● Trichomoniasis  ● Giardiasis  ●Bacterial vaginosis ●Acute ulcerative gingivitis ●Anaerobic infections including septicaemia, bacteraemia, peritonitis, brain abscess, necrotising pneumonia, osteomyelitis, puerperal sepsis, pelvic abscess, pelvic cellulitis etc.  ● Anaerobically-infected leg ulcers and pressure sores ● Acute dental infections (e.g. acute pericoronitis and acute apical infections) ● Surgical prophylaxis (prevention of postoperative infections due to anaerobic bacteria, particularly species of bacteroides and anaerobic streptococci ● Chronic symptomatic peptic ulcer disease (as an agent of triple therapy to eradicate H. pylori-the most important etiological factor of peptic ulcer)

Dosage & Administration:

Indication

Duration of dosage in days

Adult and children over 10 years

Children 7-10 years

Children 3-7 years

Children 1-3 years

Trichomoniasis

7

200 mg t.i.d or 400 mg b.i.d.

100 mg t.i.d.

100 mg b.i.d.

50 mg t.i.d.

Trichomoniasis

2

800 mg in the morning and 1.2 gm at night

.....

.....

.....

Trichomoniasis

1

2 gm as a single dose

.....

.....

.....

Invasive intestinal amoebiasis

5

800 mg t.i.d.

400 mg t.i.d.

200 mg q.i.d.

200 mg t.i.d.

Extra intestinal amoebiasis (including liver abscess) and symptomless amoebic cyst passers

5-10

400-800 mg t.i.d

200-400 mg t.i.d.

100-200 mg q.i.d.

100-200 mg t.i.d.

Giardiasis

3

2 gm once daily

1 gm once daily

600-800 mg once daily

500 mg once daily

Acute ulcerative gingivitis

3

200 mg t.i.d

100 mg t.i.d.

100 mg b.i.d

50 mg t.i.d

Acute dental infections

3-7

200 mg t.i.d

.....

.....

.....

Bacterial vaginosis

5-7

400-500 mg twice daily

.....

.....

.....

Bacterial vaginosis

1

2 gm as a single dose

.....

.....

.....

Leg ulcers and pressure sores

7

400 mg t.i.d

.....

.....

.....

Anaerobic infections

7

400-500 mg every 8 hours

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

Surgical prophylaxis

 

400-500 mg 2 hours before surgery; up to 3 further doses of 400-500 mg may be given every 8 hours for high risk procedures

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

7.5 mg/kg t.i.d.

Preparation:

Medizol 400 Tablet: Each box contains 10 X 10 tablets in blister pack.

Medizol Suspension: Each bottle contains 60 ml suspension.



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